PUS10 antibody (AA 425-475)

Catalog No. ABIN8124149

This Rabbit Polyclonal antibody specifically detects PUS10 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PUS10 antibody (AA 425-475) (ABIN8124149)

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PUS10 Antibody

Binding Specificity: AA 425-475

Purpose: PUS10 Antibody

Specificity: This antibody detects endogenous levels of PUS10 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PUS10 AA range: 425-475

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PUS10

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Alternative Name: PUS10

Background:

Background: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009],

Gene Name: PUS10 CCDC139 DOBI

Protein Name: PUS10

Gene ID: 150962

UniProt: Q3MIT2