RAPTOR antibody

Catalog No. ABIN8124237

The Rabbit Monoclonal anti-RAPTOR antibody is suitable to detect RAPTOR in samples from Human and Mouse. It has been validated for WB, ELISA, IF, IHC and IP.

Quick Overview for RAPTOR antibody (ABIN8124237)

Target: RAPTOR

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAPTOR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: AB2065

Product Details anti-RAPTOR Antibody

Purpose: Raptor Rabbit mAb

Specificity: This antibody detects endogenous levels of Raptor protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for RAPTOR

Target: RAPTOR

Alternative Name: Raptor

Background:

Synonyms: Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)

Background: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Gene Name: RPTOR KIAA1303 RAPTOR

Protein Name: Raptor

Gene ID: 57521

UniProt: Q8N122

Pathways: Warburg Effect