rala antibody (AA 170-250)

Catalog No. ABIN8124256

The Rabbit Polyclonal anti-rala antibody (ABIN8124256) specifically detects rala in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for rala antibody (AA 170-250) (ABIN8124256)

Target: rala (Ras-related Protein Ral-A (rala))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This rala antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-rala Antibody

Binding Specificity: AA 170-250

Purpose: RASL1 Antibody

Specificity: RASL1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for rala

Target: rala (Ras-related Protein Ral-A (rala))

Alternative Name: RASL1

Background:

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010],

Gene Name: RASAL1 RASAL

Protein Name: RasGAP-activating-like protein 1

Gene ID: 8437

UniProt: O95294

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome