RICTOR antibody

Catalog No. ABIN8124486

The Rabbit Monoclonal anti-RICTOR antibody is suitable to detect RICTOR in samples from Human and Mouse. It has been validated for WB, IHC, ELISA, IF and IP.

Quick Overview for RICTOR antibody (ABIN8124486)

Target: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RICTOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2134

Product Details anti-RICTOR Antibody

Purpose: Rictor Rabbit mAb

Specificity: This antibody detects endogenous levels of Rictor protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for RICTOR

Target: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Alternative Name: Rictor

Background:

Synonyms: Rapamycin-insensitive companion of mTOR, AVO3 homolog, hAVO3,

Background: RICTOR and MTOR (FRAP1, MIM 601231) are components of a protein complex that integrates nutrient-and growth factor-derived signals to regulate cell growth (Sarbassov et al. , 2004 [PubMed 15268862]) . [supplied by OMIM, Mar 2008],

Gene Name: RICTOR KIAA1999

Protein Name: Rictor

Gene ID: 253260

UniProt: Q6R327

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events