SCRIB antibody (pSer1220)

Catalog No. ABIN8124555

The Rabbit Polyclonal anti-SCRIB antibody is suitable to detect SCRIB in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for SCRIB antibody (pSer1220) (ABIN8124555)

Target: SCRIB (Scribbled Homolog (SCRIB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCRIB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SCRIB Antibody

Binding Specificity: pSer1220

Purpose: Scribble (Phospho Ser1220) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Scribble (phospho-Ser1220)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Scribble (Ser1220)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SCRIB

Target: SCRIB (Scribbled Homolog (SCRIB))

Alternative Name: Scribble

Background:

Synonyms: Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)

Background: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Gene Name: SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL

Protein Name: Scribble (Ser1220)

Gene ID: 23513

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization