SEC61B antibody (AA 30-110)

Catalog No. ABIN8124563

This Rabbit Polyclonal antibody specifically detects SEC61B in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SEC61B antibody (AA 30-110) (ABIN8124563)

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-SEC61B Antibody

Binding Specificity: AA 30-110

Purpose: SEC61B Antibody

Specificity: This antibody detects endogenous levels of human SEC61B

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SEC61B AA range: 30-110

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA(peptide)1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SEC61B

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Alternative Name: SEC61B

Background:

Synonyms: Protein transport protein Sec61 subunit beta

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma.This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],

Gene Name: SEC61B

Protein Name: SEC61B

Gene ID: 10952

UniProt: P60468

Pathways: Protein targeting to Nucleus