SESN3 antibody (AA 35-85)

Catalog No. ABIN8124638

This Rabbit Polyclonal antibody specifically detects SESN3 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for SESN3 antibody (AA 35-85) (ABIN8124638)

Target: SESN3 (Sestrin 3 (SESN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SESN3 Antibody

Binding Specificity: AA 35-85

Purpose: SESN3 Antibody

Specificity: This antibody detects endogenous levels of SESN3 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SESN3 AA range: 35-85

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: SESN3

Background:

Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],

Gene Name: SESN3 SEST3

Protein Name: SESN3

Gene ID: 143686

UniProt: P58005