SLUG antibody

Catalog No. ABIN8124777

The Rabbit Monoclonal anti-SLUG antibody is suitable to detect SLUG in samples from Human and Mouse. It has been validated for WB, ELISA, IF and IP.

Quick Overview for SLUG antibody (ABIN8124777)

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SLUG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2014

Product Details anti-SLUG Antibody

Purpose: Slug Rabbit mAb

Specificity: This antibody detects endogenous levels of Slug protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for SLUG

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Alternative Name: Slug

Background:

Synonyms: Zinc finger protein SNAI2 (Neural crest transcription factor Slug, Protein snail homolog 2)

Background: Snail family transcriptional repressor 2 (SNAI2) Homo sapiens    This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],

Gene Name: SNAI2 SLUG SLUGH

Protein Name: Slug

Gene ID: 6591

UniProt: O43623