SMOX antibody (AA 212-262)

Catalog No. ABIN8124887

This Rabbit Polyclonal antibody specifically detects SMOX in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for SMOX antibody (AA 212-262) (ABIN8124887)

Target: SMOX (Spermine Oxidase (SMOX))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMOX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMOX Antibody

Binding Specificity: AA 212-262

Purpose: SMOX Antibody

Specificity: This antibody detects endogenous levels of SMOX at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SMOX AA range: 212-262

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Alternative Name: SMOX

Background:

Background: Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters.This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012],

Gene Name: SMOX C20orf16 SMO UNQ3039/PRO9854

Protein Name: SMOX

Gene ID: 54498

UniProt: Q9NWM0