Sphingomyelin Synthase 1 antibody (pThr12)

Catalog No. ABIN8124891

The Rabbit Polyclonal anti-Sphingomyelin Synthase 1 antibody is suitable to detect Sphingomyelin Synthase 1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for Sphingomyelin Synthase 1 antibody (pThr12) (ABIN8124891)

Target: Sphingomyelin Synthase 1 (SGMS1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sphingomyelin Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Sphingomyelin Synthase 1 Antibody

Binding Specificity: pThr12

Purpose: MOB1 (Phospho Thr12) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Rat MOB1 (phospho-Thr12)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human MOB1 (Thr12)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Sphingomyelin Synthase 1

Target: Sphingomyelin Synthase 1 (SGMS1)

Alternative Name: MOB1

Background:

Synonyms: MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)

Background: The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

Protein Name: MOB1 (Thr12)

Gene ID: 55233

UniProt: Q9H8S9

Pathways: Cellular Response to Molecule of Bacterial Origin