SYK antibody (pSer297)
Quick Overview for SYK antibody (pSer297) (ABIN8124900)
Target
See all SYK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer297
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Purpose
- Syk (Phospho Ser297) Antibody
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Specificity
- This antibody detects endogenous levels of Human Syk (phospho-Ser297)
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized phosho peptide around human Syk (Ser297)
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Isotype
- IgG
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Application Notes
- WB 1:500-2000,IHC 1:50-300
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- SYK (Spleen tyrosine Kinase (SYK))
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Alternative Name
- Syk
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Background
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Synonyms: Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Gene Name: SYK
Protein Name: Syk (Ser297)
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Gene ID
- 6850
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UniProt
- P43405
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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