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SYK antibody (pTyr352)

This Rabbit Polyclonal antibody specifically detects SYK in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN8124902
$225.50
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for SYK antibody (pTyr352) (ABIN8124902)

Target

See all SYK Antibodies
SYK (Spleen tyrosine Kinase (SYK))

Reactivity

  • 195
  • 75
  • 62
  • 12
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
Human, Mouse, Rat

Host

  • 180
  • 17
  • 1
Rabbit

Clonality

  • 178
  • 20
Polyclonal

Conjugate

  • 112
  • 11
  • 9
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This SYK antibody is un-conjugated

Application

  • 157
  • 77
  • 68
  • 26
  • 22
  • 20
  • 17
  • 14
  • 14
  • 12
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 38
    • 31
    • 21
    • 15
    • 13
    • 10
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr352

    Purpose

    Syk (phospho Tyr352) Antibody

    Specificity

    Phospho-Syk (Y352) Polyclonal Antibody detects endogenous levels of Syk protein only when phosphorylated at Y352.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    Synthesized phospho-peptide around the phosphorylation site of human Syk (phospho Tyr352)

    Isotype

    IgG
  • Application Notes

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C/1 year

    Expiry Date

    12 months
  • Target

    SYK (Spleen tyrosine Kinase (SYK))

    Alternative Name

    Syk

    Background

    Synonyms: SYK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk

    Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

    Gene Name: SYK

    Protein Name: Tyrosine-protein kinase SYK

    Gene ID

    6850

    UniProt

    P43405

    Pathways

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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