SREBF2 antibody (pSer455)

Catalog No. ABIN8124981

The Rabbit Polyclonal anti-SREBF2 antibody is suitable to detect SREBF2 in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for SREBF2 antibody (pSer455) (ABIN8124981)

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SREBF2 Antibody

Binding Specificity: pSer455

Purpose: SREBP-2 (Phospho Ser455) Antibody

Specificity: This antibody detects endogenous levels of SREBP-2 (Phospho-Ser455) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human SREBP-2 (Phospho-Ser455)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Alternative Name: SREBP-2

Background:

Synonyms: Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2]

Background: This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: SREBF2 BHLHD2 SREBP2

Protein Name: SREBP-2 (Phospho-Ser455)

Gene ID: 6721

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha