Synaptophysin antibody (AA 200-313)

Catalog No. ABIN8125050

The Mouse Monoclonal anti-Synaptophysin antibody is suitable to detect Synaptophysin in samples from Human, Rat, Mouse and Cow. It has been validated for IHC.

Quick Overview for Synaptophysin antibody (AA 200-313) (ABIN8125050)

Target: Synaptophysin (SYP)

Reactivity: Human, Rat, Mouse, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1455

Product Details anti-Synaptophysin Antibody

Binding Specificity: AA 200-313

Purpose: Synaptophysin Mouse mAb (Ready to Use)

Specificity: The antibody can specifically recognize human Synaptophysin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 313 of the human Synaptophysin protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: Synaptophysin

Background:

Synonyms: Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Synaptophysin, Syp, SYPH, SYPH_HUMAN, SypI

Background: Synaptophysin is a 38 kDa membrane glycoprotein present in neuroendocrine cells. It is the most abundant synaptic vessel membrane protein, but the function remains unclear. Synaptophysin is mainly expressed in neuroendocrine cells of the human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. The antibodiy is mainly used in the classification of neuroendocrine tumors including neoplasms of epithelial type, nervous system neoplasms with neuronal differentiation and adrenocortical neoplasms.

Gene Name: SYP

Protein Name: Synaptophysin

Gene ID: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity