Synaptophysin antibody (AA 200-313)

Catalog No. ABIN8125054

The Mouse Monoclonal anti-Synaptophysin antibody (Clone AB1455) (ABIN8125054) specifically detects Synaptophysin in WB, IHC, IF and ELISA. The antibody is reactive with Human, Rat, Mouse and Cow samples.

Quick Overview for Synaptophysin antibody (AA 200-313) (ABIN8125054)

Target: Synaptophysin (SYP)

Reactivity: Human, Rat, Mouse, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Clone: AB1455

Product Details anti-Synaptophysin Antibody

Binding Specificity: AA 200-313

Purpose: Synaptophysin mouse mAb

Specificity: The antibody can specifically recognize human Synaptophysin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 313 of the human Synaptophysin protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: Synaptophysin

Background:

Synonyms: Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Synaptophysin, Syp, SYPH, SYPH_HUMAN, SypI

Background: Synaptophysin is a 38 kDa membrane glycoprotein present in neuroendocrine cells. It is the most abundant synaptic vessel membrane protein, but the function remains unclear. Synaptophysin is mainly expressed in neuroendocrine cells of the human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. The antibodiy is mainly used in the classification of neuroendocrine tumors including neoplasms of epithelial type, nervous system neoplasms with neuronal differentiation and adrenocortical neoplasms.

Gene Name: SYP

Protein Name: Synaptophysin

Gene ID: 6855

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity