TIAM1 antibody

Catalog No. ABIN8125094

This Rabbit Polyclonal antibody specifically detects TIAM1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TIAM1 antibody (ABIN8125094)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TIAM1 Antibody

Purpose: TIAM1 Antibody

Specificity: TIAM1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Alternative Name: TIAM1

Background:

Background: function:Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,similarity:Belongs to the TIAM family.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 RBD (Ras-binding) domain.,similarity:Contains 2 PH domains.,subunit:Interacts with BAIAP2.,tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.,

Gene Name: TIAM1

Protein Name: T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1)

Gene ID: 7074

UniProt: Q13009