TARDBP antibody (AA 41-90)

Catalog No. ABIN8125114

The Rabbit Polyclonal anti-TARDBP antibody (ABIN8125114) specifically detects TARDBP in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for TARDBP antibody (AA 41-90) (ABIN8125114)

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARDBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TARDBP Antibody

Binding Specificity: AA 41-90

Purpose: TADBP Antibody

Specificity: TADBP Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 41-90

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TARDBP

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Alternative Name: TADBP

Background:

Background: TAR DNA binding protein(TARDBP) Homo sapiens HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site.The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],

Gene Name: TARDBP TDP43

Protein Name: TAR DNA-binding protein 43 (TDP-43)

Gene ID: 23435

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion