TLR6 antibody

Catalog No. ABIN8125240

The Rabbit Polyclonal anti-TLR6 antibody (ABIN8125240) specifically detects TLR6 in IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TLR6 antibody (ABIN8125240)

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TLR6 Antibody

Purpose: TLR6 Antibody

Specificity: The antibody detects endogenous TLR6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of TLR6

Isotype: IgG

Application Details

Application Notes: IHC 1:200-500. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Alternative Name: TLR6

Background:

Synonyms: Toll-like receptor 6, CD286

Background: The protein encoded byThis gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011],

Gene Name: TLR6

Protein Name: Toll-like receptor 6

Gene ID: 10333

UniProt: Q9Y2C9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades