TOPBP1 antibody (pSer1159)

Catalog No. ABIN8125251

The Rabbit Polyclonal anti-TOPBP1 antibody is suitable to detect TOPBP1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for TOPBP1 antibody (pSer1159) (ABIN8125251)

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOPBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TOPBP1 Antibody

Binding Specificity: pSer1159

Purpose: TOPBP1 (Phospho Ser1159) Antibody

Specificity: This antibody detects endogenous levels of TOPBP1 (Phospho-Ser1159) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human TOPBP1 (Phospho-Ser1159)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Alternative Name: TOPBP1

Background:

Synonyms: DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)

Background: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008],

Gene Name: TOPBP1 KIAA0259

Protein Name: TOPBP1 (Phospho-Ser1159)

Gene ID: 11073

UniProt: Q92547

Pathways: Chromatin Binding