STING/TMEM173 antibody (pSer366)

Catalog No. ABIN8125357

The Rabbit Polyclonal anti-STING/TMEM173 antibody (ABIN8125357) specifically detects STING/TMEM173 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for STING/TMEM173 antibody (pSer366) (ABIN8125357)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STING/TMEM173 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STING/TMEM173 Antibody

Binding Specificity: pSer366

Purpose: STING (Phospho Ser366) Antibody

Specificity: This antibody detects endogenous levels of STING (Phospho-Ser366) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human STING (Phospho-Ser366)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Alternative Name: STING

Background:

Synonyms: Transmembrane protein 173 (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Stimulator of interferon genes protein) (hSTING)

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Gene Name: TMEM173 ERIS MITA STING

Protein Name: STING (Phospho-Ser366)

Gene ID: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response