TP53BP2 antibody

Catalog No. ABIN8125484

This Rabbit Monoclonal antibody specifically detects TP53BP2 in WB, IHC, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for TP53BP2 antibody (ABIN8125484)

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AB2239

Product Details anti-TP53BP2 Antibody

Purpose: 53BP2/ASPP2 Rabbit mAb

Specificity: This antibody detects endogenous levels of 53BP2/ASPP2 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 |

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: 53BP2/ASPP2

Background:

Synonyms: TP53BP2, ASPP2, BBP, Apoptosis-stimulating of p53 protein 2 , Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2,

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: TP53BP2, ASPP2, BBP

Protein Name: 53BP2/ASPP2

Gene ID: 7159

UniProt: Q13625