TYK2 antibody (pTyr292)

Catalog No. ABIN8125503

The Rabbit Polyclonal anti-TYK2 antibody is suitable to detect TYK2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for TYK2 antibody (pTyr292) (ABIN8125503)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TYK2 Antibody

Binding Specificity: pTyr292

Purpose: Tyk 2 (Phospho Tyr292) Antibody

Specificity: This antibody detects endogenous levels of Human Tyk 2 (Phospho Tyr292)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Alternative Name: Tyk 2

Background:

Synonyms: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

Gene Name: TYK2

Protein Name: Tyk 2 (Phospho Tyr292)

Gene ID: 7297

UniProt: P29597

Pathways: JAK-STAT Signaling, Hepatitis C