ULBP1 antibody

Catalog No. ABIN8125598

This Rabbit Polyclonal antibody specifically detects ULBP1 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ULBP1 antibody (ABIN8125598)

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULBP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ULBP1 Antibody

Purpose: N2DL1 Antibody

Specificity: N2DL1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Alternative Name: N2DL1

Background:

Background: The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

Gene Name: ULBP1 N2DL1 RAET1I

Protein Name: NKG2D ligand 1 (N2DL-1) (NKG2DL1) (ALCAN-beta) (Retinoic acid early transcript 1I) (UL16-binding protein 1)

Gene ID: 80329

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process