TUSC1 antibody (AA 131-212)

Catalog No. ABIN762641

There are 2+ publications for this product available. The Rabbit Polyclonal anti-TUSC1 antibody is suitable to detect TUSC1 in samples from Mouse. It has been validated for WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for TUSC1 antibody (AA 131-212) (ABIN762641)

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUSC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TUSC1 Antibody

Binding Specificity: AA 131-212

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUSC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TUSC1 antibody (ABIN762641)

Kanda, Shimizu, Nomoto, Hibino, Oya, Takami, Kobayashi, Yamada, Inokawa, Tanaka, Fujii, Sugimoto, Koike, Fujiwara, Kodera: "Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer." in: Journal of surgical oncology, Vol. 110, Issue 2, pp. 136-44, (2014) (PubMed).

Shimizu, Kanda, Nomoto, Oya, Takami, Hibino, Suenaga, Inokawa, Hishida, Takano, Nishikawa, Yamada, Fujii, Nakayama, Sugimoto, Koike, Fujiwara, Kodera: "Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma." in: Oncology reports, Vol. 31, Issue 3, pp. 1305-13, (2014) (PubMed).

Target Details for TUSC1

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Alternative Name: Tusc1

Background:

Synonyms: TSG9, TSG-9, Tumor suppressor candidate gene 1 protein, TUSC1

Background: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.

Gene ID: 286319

UniProt: Q2TAM9