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Retinoblastoma Binding Protein 4 antibody (AA 231-330) (FITC)

This anti-Retinoblastoma Binding Protein 4 antibody is a Rabbit Polyclonal antibody detecting Retinoblastoma Binding Protein 4 in IF (cc) and IF (p). Suitable for Mouse and Rat.
Catalog No. ABIN762873

Quick Overview for Retinoblastoma Binding Protein 4 antibody (AA 231-330) (FITC) (ABIN762873)

Target

See all Retinoblastoma Binding Protein 4 (RBBP4) Antibodies
Retinoblastoma Binding Protein 4 (RBBP4)

Reactivity

  • 54
  • 44
  • 40
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Mouse, Rat

Host

  • 59
  • 8
  • 2
Rabbit

Clonality

  • 49
  • 20
Polyclonal

Conjugate

  • 34
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Retinoblastoma Binding Protein 4 antibody is conjugated to FITC

Application

  • 31
  • 22
  • 18
  • 17
  • 13
  • 13
  • 10
  • 9
  • 7
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 231-330

    Cross-Reactivity

    Mouse, Rat

    Predicted Reactivity

    Human,Chicken,Rabbit,Zebrafish

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human RbAp48

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Retinoblastoma Binding Protein 4 (RBBP4)

    Alternative Name

    RbAp48

    Background

    Synonyms: RBBP4_HUMAN, Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48.

    Background: RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly, chromatin remodeling, and histone deacetylation. These complexes include Chromatin Assembly Factor 1 (CAF1), which is required for chromatin assembly following DNA replication and repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and subsequent transcriptional repression, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, and the PRC2 complex, which promotes repression of homeotic genes during development. RpAp48 also interacts with the retinoblastoma protein, and with SPEN/MINT and BRCA1. It is also a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells.

    Gene ID

    5928

    Pathways

    Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus
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