HNF1A antibody

Catalog No. ABIN781212

The Mouse Monoclonal anti-HNF1A antibody is suitable to detect HNF1A in samples from Human. It has been validated for WB and ELISA.

Quick Overview for HNF1A antibody (ABIN781212)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HNF1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HNF1A Antibody

Specificity: Nucleus

Purification: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of Human HNF1A (N-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100 - 1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1A

Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.

Molecular Weight: 40kDa

NCBI Accession: NM_000545

Pathways: Hormone Transport, Carbohydrate Homeostasis