HNF1A antibody
Quick Overview for HNF1A antibody (ABIN781212)
Target
See all HNF1A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Nucleus
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Purification
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human HNF1A (N-terminus).
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Isotype
- IgG
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Application Notes
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100 - 1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Alternative Name
- HNF1A
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Background
- The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
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Molecular Weight
- 40kDa
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NCBI Accession
- NM_000545
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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