CRP antibody
Quick Overview for CRP antibody (ABIN781723)
Target
See all CRP AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody detects C-reactive protein (CRP).
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Cross-Reactivity (Details)
- Species reactivity (tested):Pig
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Purification
- Purified
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Immunogen
- Purified porcine CRP
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline pH 7.2 (PBS), and 0.09 % sodium azide as a preservative. No stabilizing protein has been added.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CRP (C-Reactive Protein (CRP))
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Background
- Monoclonal antibody PC1 recognizes porcine C-reactive protein (CRP). CRP belongs to a highly conserved phylogenetically ancient family called pentraxins, which have five identical non-covalently linked subunits. Native CRP in its pentameric form has a molecular weight of approximately 115 kDa. As in humans, CRP is an acute-phase protein in pigs. It has been suspected to be directly involved in the pathogenesis of ischemic diseases through the activation of the complement system. CRP levels have been measured in porcine serum. Median levels in specific pathogen-free animals were 5 μg/mL and increased 40- to 70-fold due to inflammation or infection with Mycoplasma hyopneumoniae.Synonyms: C Reactive Protein, PTX1, Pentraxin-related
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Gene ID
- 396842
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NCBI Accession
- NP_999009
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UniProt
- O19062
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Pathways
- Carbohydrate Homeostasis
Target
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