PRR5 antibody (C-Term)

Catalog No. ABIN783442

This Rabbit Polyclonal antibody specifically detects PRR5 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRR5 antibody (C-Term) (ABIN783442)

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRR5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PRR5 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects PRR5 at C-term. PRR5 antibody is predicted to not cross-react with other Protor protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 20 amino acid peptide near the carboxy terminus of human PRR5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for PRR5

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Alternative Name: PRR5

Background: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-β expression.Synonyms: PROTOR1, Proline-rich protein 5, Protein observed with Rictor-1, Protor-1

Gene ID: 55615

NCBI Accession: NP_001017528

UniProt: P85299

Pathways: PI3K-Akt Signaling