AP3M1 antibody (C-Term)

Catalog No. ABIN783506

The Rabbit Polyclonal anti-AP3M1 antibody is suitable to detect AP3M1 in samples from Human, Mouse and Rat. It has been validated for WB and EIA.

Quick Overview for AP3M1 antibody (C-Term) (ABIN783506)

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-AP3M1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects AP3 complex subunit mu-1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: Raised against a 15 amino acid peptide near the carboxy terminus of human AP3M1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for AP3M1

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Alternative Name: AP3 Complex Subunit mu-1

Background: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.Synonyms: AP-3 adapter complex mu3A subunit, AP3M1, Adapter-related protein complex 3 mu-1 subunit, Mu-adaptin 3A, Mu3A-adaptin

Gene ID: 26985

NCBI Accession: NP_036227

UniProt: Q9Y2T2