SYTL5 antibody (N-Term)

Catalog No. ABIN783534

The Rabbit Polyclonal anti-SYTL5 antibody (ABIN783534) specifically detects SYTL5 in WB and EIA. The antibody is reactive with Rat, Human and Mouse samples.

Quick Overview for SYTL5 antibody (N-Term) (ABIN783534)

Target: SYTL5 (Synaptotagmin-Like 5 (SYTL5))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYTL5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SYTL5 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects SYTL5 at N-term. Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human SYTL5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SYTL5

Target: SYTL5 (Synaptotagmin-Like 5 (SYTL5))

Alternative Name: SYTL5

Background: SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.Synonyms: SLP5, Synaptotagmin-like protein 5

Gene ID: 94122

NCBI Accession: NP_001156807

UniProt: Q8TDW5