SYTL5 antibody (N-Term)

Catalog No. ABIN6991559

Product Details anti-SYTL5 Antibody

Target: SYTL5 (Synaptotagmin-Like 5 (SYTL5))

Binding Specificity: AA 30-80, N-Term

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYTL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.

Purification: SYTL5 Antibody is affinity chromatography purified via peptide column.

Immunogen: SYTL5 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SYTL5. The immunogen is located within amino acids 30 - 80 of SYTL5.

Isotype: IgG

Application Details

Application Notes: SYTL5 antibody can be used for detection of SYTL5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYTL5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SYTL5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SYTL5

Target: SYTL5 (Synaptotagmin-Like 5 (SYTL5))

Alternative Name: SYTL5 (SYTL5 Products)

Synonyms: slp5 antibody, ENSMUSG00000054453 antibody, synaptotagmin like 5 antibody, synaptotagmin-like 5 antibody, SYTL5 antibody, Sytl5 antibody

Background: SYTL5 Antibody: SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.

Gene ID: 94122

NCBI Accession: NP_620135

UniProt: Q8TDW5