SIRT5 antibody (C-Term)

Catalog No. ABIN783614

The Chicken Polyclonal anti-SIRT5 antibody has been validated for WB and EIA. It is suitable to detect SIRT5 in samples from Human and Mouse.

Quick Overview for SIRT5 antibody (C-Term) (ABIN783614)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reactivity: Human, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SIRT5 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human SIRT5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5

Background: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.Synonyms: NAD-dependent deacetylase sirtuin-5, SIR2-like protein 5, SIR2L5, SIRT-5, sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), sirtuin 5, sirtuin type 5, sirtuin-5

Gene ID: 23408

NCBI Accession: NP_036373

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome