CCDC106 antibody (C-Term)

Catalog No. ABIN783671

The Rabbit Polyclonal anti-CCDC106 antibody is suitable to detect CCDC106 in samples from Human, Mouse and Rat. It has been validated for WB, IF and EIA.

Quick Overview for CCDC106 antibody (C-Term) (ABIN783671)

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC106 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-CCDC106 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human CCDC106

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Alternative Name: CCDC106

Background: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.Synonyms: Coiled-coil domain-containing protein 106

Gene ID: 29903

NCBI Accession: NP_037433

UniProt: Q9BWC9