ICAM1 antibody

Catalog No. ABIN783846

The Rabbit Polyclonal anti-ICAM1 antibody (ABIN783846) specifically detects ICAM1 in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ICAM1 antibody (ABIN783846)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ICAM1 Antibody

Specificity: This antibody recognizes ~89-92 kDa ICAM-1.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: CD54 / ICAM1

Background: Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. The family contains NCAM (for neuronal cell adhesion molecule), ICAM (for intercellular adhesion molecule), VCAM (vascular cell adhesion molecule), PECAM-1 (platelet/endothelial cell adhesion molecule-1), etc. ICAM-1, also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2a1 and B2aM integrins.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor

Gene ID: 3383

NCBI Accession: NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling