C3 antibody
Quick Overview for C3 antibody (ABIN784157)
Target
See all C3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody detects Human Complement 3c, a polypeptide fragment which is present in C3. Minimal cross reactivity with related serum proteins.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Protein G Chromatography
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Immunogen
- Human Complement 3c
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- C3 (Complement Component 3 (C3))
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Alternative Name
- Complement C3
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Background
- Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacteria infection.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
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Gene ID
- 718
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NCBI Accession
- NP_000055
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Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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