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IL12A antibody
IL12A
Reactivity: Human, Dog, Pig
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-IL12A Antibody
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Target
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IL12A
(Interleukin 12 alpha (IL12A))
Reactivity
All reactivities for IL12A antibodies
Human, Dog, Pig
Host
All hosts for IL12A antibodies
Goat
Clonality
All clonalities for IL12A antibodies
Polyclonal
Conjugate
All conjugates for IL12A antibodies
This IL12A antibody is un-conjugated
Application
All applications for IL12A antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
Recognizes Interleukin-12 alpha / IL12A.
Cross-Reactivity (Details)
Species reactivity (expected):Canine (Dog), Pig. Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide - KLH conjugated of Human IL12A
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Discover our top product IL12A Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
Target Details for IL12A
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Target
IL12A
(Interleukin 12 alpha (IL12A))
Alternative Name
Interleukin-12 alpha / IL12A (IL12A Products )
Synonyms
CLMF antibody, IL-12A antibody, NFSK antibody, NKSF1 antibody, P35 antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p35 antibody, Il-12 p35 antibody, IL12p40 antibody, IL12 antibody, IL-12 p35 antibody, interleukin 12A antibody, interleukin 12B antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12A antibody, IL12B antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
Background
Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
Gene ID
3592
NCBI Accession
NP_000873
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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