SPTAN1 antibody (AA 676-1043)

Catalog No. ABIN789013

This Mouse Monoclonal antibody specifically detects SPTAN1 in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SPTAN1 antibody (AA 676-1043) (ABIN789013)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SPTAN1 Antibody

Binding Specificity: AA 676-1043

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Aff - Purified

Immunogen: Recombinant protein construct containing the 7th, 8th and 9th spectrin repeats of human alpha-II spectrin (AA 676-1043. This construct was expressed in and purified from E. coli.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Background: The spectrin family of proteins were originally discovered as major components of the submembraneous cytoskeleton of osmotically lyzed red blood cells. Work by Levine and Willard described a pair of about ~240-260 kDa molecular weight bands which were transported at the slowest rate along mammalian axons. They named these proteins

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization