FGFR1 antibody (AA 179-195)

Catalog No. ABIN790693

This Mouse Monoclonal antibody specifically detects FGFR1 in WB, IHC, IP and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FGFR1 antibody (AA 179-195) (ABIN790693)

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGFR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: M17D10

Product Details anti-FGFR1 Antibody

Binding Specificity: AA 179-195

Brand: IHC-plus™

Specificity: Reacts with both alpha and beta isoforms. Epitope is within the sequence pro179 to lys195 in Ig loop II.

Purification: Protein G purified

Immunogen: Recombinant human ectodomain of FGFr1~ expressed in E. coli from pro23 to his415, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), IP, WB (1 μg/mL)

Usage: Western blotting: at 1 μg/mL recognizes 10 ng recombinant bacterial, baculoviral, or native FGFr1. Immunoprecipitation: native, recombinant, and ligand-labeled FGFr1. IHC-P: human FFPE tissues.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Aliquot to Avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Alternative Name: FGFR1

Background: Name/Gene ID: FGFR1
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD

Gene ID: 2260

UniProt: P11362

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins