FANCG antibody (pSer383) (Biotin)

Catalog No. ABIN800810

The Rabbit Polyclonal anti-FANCG antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect FANCG in samples from Human.

Quick Overview for FANCG antibody (pSer383) (Biotin) (ABIN800810)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCG antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FANCG Antibody (Biotin)

Binding Specificity: pSer383

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FANCG around the phosphorylation site of Ser383

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG

Background:

Synonyms: FANCG phospho S383, p-FANCG phospho S383, DNA repair protein XRCC9, DNA-repair protein XRCC9, FAG, Fanconi anaemia complementation group G, Protein FACG, X ray repair, complementing defective, in Chinese hamster cells 9, XRCC9.

Background: FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.

Gene ID: 2189

Pathways: DNA Damage Repair