JunB antibody (pSer259) (Biotin)

Catalog No. ABIN802445

The Rabbit Polyclonal anti-JunB antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect JunB in samples from Human.

Quick Overview for JunB antibody (pSer259) (Biotin) (ABIN802445)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JunB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-JunB Antibody (Biotin)

Binding Specificity: pSer259

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human JunB around the phosphorylation site of Ser259 [PV(p-S)PI]

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Alternative Name: JunB

Background:

Synonyms: Activator protein 1, AP 1, AP1, Jun B, Jun B proto oncogene, Jun B protooncogene, JunB proto oncogene, JunB protoncogene 9, JunB protooncogene, Transcription factor jun B, Transcription factor junB.

Background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Gene ID: 3726