ATF2 antibody

Catalog No. ABIN865467

The Mouse Monoclonal anti-ATF2 antibody (Clone 4F12) (ABIN865467) specifically detects ATF2 in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for ATF2 antibody (ABIN865467)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4F12

Product Details anti-ATF2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ATF2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. Tissue specificity: Abundant expression seen in the brain. Synonyms: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

Molecular Weight: 55kDa

Gene ID: 1386

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades