p53 antibody (N-Term)
Quick Overview for p53 antibody (N-Term) (ABIN870342)
Target
See all p53 (TP53) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 46-67, N-Term
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Purpose
- Anti-p53
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Specificity
- P53
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Immunogen
- Peptide derived from N-terminal sequence of human p53. Antibody recognizes the epitope between Ser46 - Pro67.
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Isotype
- IgG
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Application Notes
- 1:100 - 500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- +2 °C to +8 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Alternative Name
- p53
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Background
- P53 (tumor supressor protein) is general marker of cell proliferation. Its enhanced expression is in most cases related to cancer (e.g. can be used as a valuable prognostic marker of conventional renal cell carcinoma). This clone is specially produced for IHC-P applications.
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UniProt
- P04637
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Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
Target
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