NGFR antibody (AA 202-215)

Catalog No. ABIN870688

This Goat Polyclonal antibody specifically detects NGFR in WB and ELISA. It exhibits reactivity toward Rat.

Quick Overview for NGFR antibody (AA 202-215) (ABIN870688)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-NGFR Antibody

Binding Specificity: AA 202-215

Purpose: p75NTR / CD271 (aa202-215)

Sequence: PEGSDSTAPS TQEP

Specificity: This antibody is expected to recognize the extracellular domain of p75NTR.

Cross-Reactivity: Cow, Human, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-PEGSDSTAPSTQEP, from the internal region of the protein sequence according to NP_002498.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 75 kDa band observed in Rat Heart lysates (calculated MW of 45.2 kDa according to Human NP_002498.1 and 45.4 kDa according to Rat NP_036742.2. The observed molecular weight corresponds to earlier findings in literature with different an

Peptide ELISA: antibody detection limit dilution 1:4000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Alternative Name: NGFR

Background: NGFR, nerve growth factor receptor, CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, NGF receptor, OTTHUMP00000220319, TNFR superfamily, member 16, low affinity nerve growth factor receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve grow

Molecular Weight: 45.2kDa

Gene ID: 4804, 18053, 24596

NCBI Accession: NP_002498

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding