SLC12A3 antibody (AA 951-1021)

Catalog No. ABIN872340

Cited in 2+ publications. The Rabbit Polyclonal anti-SLC12A3 antibody (ABIN872340) specifically detects SLC12A3 in ELISA, FACS, IF (cc), IF (p), IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SLC12A3 antibody (AA 951-1021) (ABIN872340)

Target: SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SLC12A3 Antibody

Binding Specificity: AA 951-1021

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC12A3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SLC12A3 antibody (ABIN872340)

Turco, Lam, Rule, Denic, Lieske, Miller, Larson, Kremers, Jayachandran: "Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys." in: Journal of extracellular vesicles, Vol. 5, pp. 29642, (2016) (PubMed).

Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." in: Biology of sex differences, Vol. 6, pp. 2, (2015) (PubMed).

Target Details for SLC12A3

Target: SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))

Alternative Name: Slc12a3

Background:

Synonyms: NCC, TSC, NCCT, Solute carrier family 12 member 3, Na-Cl cotransporter, Na-Cl symporter, Thiazide-sensitive sodium-chloride cotransporter, SLC12A3

Background: Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.

Gene ID: 6559

UniProt: P55017