NLRP7 antibody (AA 901-980)

Catalog No. ABIN872347

This Rabbit Polyclonal antibody specifically detects NLRP7 in ELISA, WB, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for NLRP7 antibody (AA 901-980) (ABIN872347)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NLRP7 Antibody

Binding Specificity: AA 901-980

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Alternative Name: NLRP7

Background:

Synonyms: CLR19.4, FLJ94610, HYDM, NACHT, leucine rich repeat and PYD containing 7, NACHT, LRR and PYD containing protein 7, NACHT, LRR and PYD domains containing protein 7, NACHT, LRR and PYD domains-containing protein 7, NALP7, NALP7_HUMAN, NLR family, pyrin domain containing 7, NLRP7, NOD12, Nucleotide-binding oligomerization domain protein 12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7, PAN7, PYPAF3, PYRIN-containing APAF1-like protein 3.

Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Gene ID: 199713

Pathways: Inflammasome