MORF4L1 antibody (AA 261-360)
Quick Overview for MORF4L1 antibody (AA 261-360) (ABIN872616)
Target
See all MORF4L1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 261-360
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Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Zebrafish
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Mortality factor 4-like protein 1/SEN1
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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Alternative Name
- Mortality factor 4-like protein 1
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Background
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Synonyms: Cell senescence related gene complementation group B, Cellular senescence related protein 1, CSR, CSRB, MORF 4, MORF4, MORF4 protein, Mortality factor 4, SEN 1, SEN, Senescence cellular related 1, Senescence related cellular 1, Transcription factor like protein MORF4, MO4L1_HUMAN, Mortality factor 4-like protein 1, MORF-related gene 15 protein, Protein MSL3-1, Transcription factor-like protein MRG15.
Background: Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to one of several complementation groups. SEN1 or MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. It is capable of reversing the immortal phenotype of a subset of immortal cells. Overexpression of SEN1 in HeLa cells ultimately caused abnormal nuclear morphology and cell death.
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Gene ID
- 10934
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Pathways
- Chromatin Binding
Target
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