AGFG2 antibody (AA 381-481)

Catalog No. ABIN872890

This Rabbit Polyclonal antibody specifically detects AGFG2 in WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for AGFG2 antibody (AA 381-481) (ABIN872890)

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AGFG2 Antibody

Binding Specificity: AA 381-481

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AGFG2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AGFG2

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Alternative Name: AGFG2

Background:

Synonyms: Agfg2, AGFG2_HUMAN, Arf GAP domain and FG repeats containing protein 2, Arf-GAP domain and FG repeats-containing protein 2, HIV-1 Rev-binding protein-like protein, HIV1 Rev binding protein like protein, HRBL, Nucleoporin, RAB-R, RABR, Rev/Rex activation domain-binding protein related.

Background: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.