SRRM4 antibody (AA 451-611)

Catalog No. ABIN873105

The Rabbit Polyclonal anti-SRRM4 antibody (ABIN873105) specifically detects SRRM4 in WB, IF (cc), IF (p), IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SRRM4 antibody (AA 451-611) (ABIN873105)

Target: SRRM4 (Serine/arginine Repetitive Matrix 4 (SRRM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SRRM4 Antibody

Binding Specificity: AA 451-611

Purpose: SRRM4 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRRM4

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SRRM4

Target: SRRM4 (Serine/arginine Repetitive Matrix 4 (SRRM4))

Alternative Name: SRRM4

Background:

Synonyms: Neural-specic serine/arginine repetitive splicing factor of 100 kDa, Neural-specic SR-related protein of 100 kDa, nSR100, Serine/arginine repetitive matrix protein 4, Srrm4, SRRM4_HUMAN.

Background: Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.

Pathways: Sensory Perception of Sound