NLRP10 antibody (AA 401-500)

Catalog No. ABIN873152

The Rabbit Polyclonal anti-NLRP10 antibody has been validated for ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect NLRP10 in samples from Human.

Quick Overview for NLRP10 antibody (AA 401-500) (ABIN873152)

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP10 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NLRP10 Antibody

Binding Specificity: AA 401-500

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP10

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Alternative Name: NLRP10

Background:

Synonyms: CLR11.1, NACHT, leucine rich repeat and PYD containing 10, NACHT, LRR and PYD domains containing protein 10, NACHT, LRR and PYD domains-containing protein 10, NAL10_HUMAN, NALP10, NLR family, pyrin domain containing 10, Nlrp10, NOD8,Nucleotide-binding oligomerization domain protein 8, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10, PAN5, PYNOD.

Background: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle.

Gene ID: 338322

Pathways: Inflammasome