PDCD6 antibody (AA 91-191)

Catalog No. ABIN873280

This Rabbit Polyclonal antibody specifically detects PDCD6 in ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for PDCD6 antibody (AA 91-191) (ABIN873280)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PDCD6 Antibody

Binding Specificity: AA 91-191

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDCD6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6

Background:

Synonyms: ALG 2, ALG2, Apoptosis linked gene 2, Apoptosis linked gene 2 protein, Apoptosis-linked gene 2 protein, MA 3, MA3, MGC111017, MGC119050, MGC9123, PDCD 6, Pdcd6, PDCD6_HUMAN, PEF 1B, PEF1B, Probable calcium binding protein ALG 2, Probable calcium binding protein ALG2, Probable calcium-binding protein ALG-2, Programmed cell death 6, Programmed cell death protein 6, PS 2, PS2.

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012].

Gene ID: 10016

Pathways: Positive Regulation of Endopeptidase Activity